A one-pot synthesis of functionalized azadienes from 2-hydroxypyridine, activated acetylenes and alkyl isocyanides

One-pot synthesis of functionalized thiazolidine-4-ones from thiosemicarbazone derivatives and activated acetylenes in water as a green solvent

Some 2-iminothiazolidin-4-ones have been synthesized by the reaction of dialkyl acetylenedicarboxylates with thiosemicarbazones. The reaction was performed in the presence of 10 mol% of triphenylphosphine and tetrabutylammonium bromide as a phase transfer catalyst in water as a green solvent. All the synthesized compounds were characterized by their physical and spectral data.

One-pot synthesis of functionalized thiazolidine-4-ones from thiosemicarbazone derivatives and activated acetylenes in water as a green solvent

Some 2-iminothiazolidin-4-ones have been synthesized by the reaction of dialkyl acetylenedicarboxylates with thiosemicarbazones. The reaction was performed in the presence of 10 mol% of triphenylphosphine and tetrabutylammonium bromide as a phase transfer catalyst in water as a green solvent. All the synthesized compounds were characterized by their physical and spectral data.

A One-Pot Synthesis of Highly Functionalized Ketenimines by a Three-component 2-Thioxothiazolidin-4-one, Alkyl Isocyanides and Dialkyl Acetylenedicarboxylates

The 1:1 reactive intermediates produced in the reaction between alkyl isocyanides and dialkyl acetylenedicarboxylates were trapped with 2-thioxothiazolidin-4-one to generate to highly functionalized ketenimines. A series of new 2-thioxothiazolidin-4-one derivatives were synthesized in moderate yields. The advantages of the present method include good functional group tolerance and simple experi...

one-pot synthesis of functionalized thiazolidine-4-ones from thiosemicarbazone derivatives and activated acetylenes in water as a green solvent

some 2-iminothiazolidin-4-ones have been synthesized by the reaction of dialkyl acetylenedicarboxylates with thiosemicarbazones. the reaction was performed in the presence of 10 mol% of triphenylphosphine and tetrabutylammonium bromide as a phase transfer catalyst in water as a green solvent. all the synthesized compounds were characterized by their physical and spectral data.

a one-pot synthesis of highly functionalized ketenimines by a three-component 2-thioxothiazolidin-4-one, alkyl isocyanides and dialkyl acetylenedicarboxylates